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Yun Chen Selected Research

Enzymes

1/2024M6A methylation of FKFB3 reduced pyroptosis of gastric cancer by NLRP3.
11/2023Mycobacterium tuberculosis Rv2653 Protein Promotes Inflammation Response by Enhancing Glycolysis.
10/2023microRNA-143 interferes the EGFR-stimulated glucose metabolism to re-sensitize 5-FU resistant colon cancer cells via targeting hexokinase 2.
4/2023Constructed Tumor-Targeted and MMP-2 Biocleavable Antibody Conjugated Silica Nanoparticles for Efficient Cancer Therapy.
12/2022PD-L1 blockade liberates intrinsic antitumourigenic properties of glycolytic macrophages in hepatocellular carcinoma.
6/2022[Mechanism of tanshinone II A inhibiting myocardial remodeling by Galectin-3].
1/2021Yeast optimizes metal utilization based on metabolic network and enzyme kinetics.
11/2020miR-124-3p increases in high glucose induced osteocyte-derived exosomes and regulates galectin-3 expression: A possible mechanism in bone remodeling alteration in diabetic periodontitis.
1/2020Polymorphisms of Drug-Metabolizing Enzymes and Transporters Contribute to the Individual Variations of Erlotinib Steady State Trough Concentration, Treatment Outcomes, and Adverse Reactions in Epidermal Growth Factor Receptor-Mutated Non-Small Cell Lung Cancer Patients.
1/2020A self-assembled pH/enzyme dual-responsive prodrug with PEG deshielding for multidrug-resistant tumor therapy.
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Yun Chen Research Topics

Disease

286Neoplasms (Cancer)
05/2024 - 02/2002
56Breast Neoplasms (Breast Cancer)
04/2024 - 07/2010
51Inflammation (Inflammations)
06/2024 - 12/2003
40Neoplasm Metastasis (Metastasis)
03/2024 - 09/2011
36Infections
04/2024 - 12/2009
27Esophageal Squamous Cell Carcinoma
03/2024 - 12/2013
26Erectile Dysfunction
01/2024 - 10/2005
21Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2024 - 08/2011
20Glioma (Gliomas)
09/2020 - 03/2004
19Type 2 Diabetes Mellitus (MODY)
01/2022 - 12/2008
18Fibrosis (Cirrhosis)
06/2024 - 12/2003
17Esophageal Neoplasms (Esophageal Cancer)
03/2024 - 12/2013
17Carcinoma (Carcinomatosis)
12/2023 - 06/2003
16Stomach Neoplasms (Stomach Cancer)
03/2024 - 01/2015
15Hypoxia (Hypoxemia)
03/2024 - 03/2014
15Hemorrhage
02/2024 - 02/2010
15Carcinogenesis
02/2024 - 04/2014
15Hepatocellular Carcinoma (Hepatoma)
01/2023 - 10/2009
14Insulin Resistance
12/2023 - 12/2008
14Body Weight (Weight, Body)
10/2023 - 05/2004
13Alzheimer Disease (Alzheimer's Disease)
04/2024 - 01/2019
12Wounds and Injuries (Trauma)
05/2024 - 03/2015
12Neuroblastoma
08/2021 - 09/2002
11Colorectal Neoplasms (Colorectal Cancer)
05/2024 - 01/2017
11Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2023 - 07/2012
10Mitochondrial Diseases (Mitochondrial Disease)
05/2024 - 04/2012
10Necrosis
01/2024 - 12/2003
10Hypertension (High Blood Pressure)
08/2023 - 04/2010
10Obesity
02/2023 - 12/2008
9Neurodegenerative Diseases (Neurodegenerative Disease)
05/2024 - 05/2010
9Diabetes Mellitus
10/2023 - 03/2007
8Stroke (Strokes)
11/2023 - 07/2004
8Leukemia
11/2023 - 06/2005
8Colonic Neoplasms (Colon Cancer)
10/2023 - 11/2006
8Cardiovascular Diseases (Cardiovascular Disease)
02/2023 - 05/2012
7Nasopharyngeal Carcinoma
05/2024 - 05/2005
7COVID-19
04/2024 - 01/2021
7Osteoporosis
04/2024 - 09/2011
7Lung Neoplasms (Lung Cancer)
04/2024 - 05/2016
7Pain (Aches)
03/2024 - 04/2016
7Atrophy
03/2024 - 12/2003
7Hypertrophy
01/2023 - 06/2015

Drug/Important Bio-Agent (IBA)

91Proteins (Proteins, Gene)FDA Link
05/2024 - 05/2005
48Biomarkers (Surrogate Marker)IBA
06/2024 - 02/2014
36MicroRNAs (MicroRNA)IBA
12/2023 - 08/2009
25Therapeutic UsesIBA
01/2024 - 11/2002
22Doxorubicin (Adriamycin)FDA LinkGeneric
04/2024 - 06/2005
20Glucose (Dextrose)FDA LinkGeneric
12/2023 - 08/2010
20Insulin (Novolin)FDA Link
10/2023 - 10/2009
19Peptides (Polypeptides)IBA
04/2024 - 04/2010
19Paclitaxel (Taxol)FDA LinkGeneric
02/2024 - 09/2013
18Messenger RNA (mRNA)IBA
01/2024 - 06/2003
17Long Noncoding RNAIBA
05/2024 - 01/2015
16LipidsIBA
01/2024 - 02/2007
16RNA (Ribonucleic Acid)IBA
01/2023 - 03/2013
15Cisplatin (Platino)FDA LinkGeneric
03/2024 - 10/2012
14CytokinesIBA
04/2024 - 11/2002
14EnzymesIBA
01/2024 - 05/2005
14Reactive Oxygen Species (Oxygen Radicals)IBA
10/2022 - 09/2010
13HydrogelsIBA
04/2024 - 11/2016
13Phosphotransferases (Kinase)IBA
04/2024 - 04/2013
13VaccinesIBA
12/2023 - 02/2005
12AntigensIBA
02/2024 - 05/2005
12InflammasomesIBA
01/2024 - 01/2018
10Immune Checkpoint InhibitorsIBA
03/2024 - 01/2020
10CateninsIBA
12/2023 - 03/2014
10CollagenIBA
11/2023 - 04/2010
10ErbB Receptors (EGF Receptor)IBA
10/2023 - 01/2019
10Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2023 - 03/2004
9AntioxidantsIBA
05/2024 - 06/2012
9Caspase 3 (Caspase-3)IBA
04/2024 - 05/2004
9Fluorouracil (Carac)FDA LinkGeneric
12/2023 - 12/2016
9Interleukin-6 (Interleukin 6)IBA
11/2023 - 09/2011
9CholesterolIBA
07/2023 - 02/2007
9Antiviral Agents (Antivirals)IBA
01/2023 - 05/2007
9Member 1 Subfamily B ATP Binding Cassette TransporterIBA
01/2020 - 10/2012
8Adenosine Triphosphate (ATP)IBA
05/2024 - 04/2012
8Membrane Proteins (Integral Membrane Proteins)IBA
05/2024 - 05/2005
8Amyloid (Amyloid Fibrils)IBA
04/2024 - 01/2020
8Galectin 3 (LGALS3)IBA
03/2024 - 02/2002
8LipopolysaccharidesIBA
01/2024 - 02/2009
8LigandsIBA
11/2023 - 07/2015
8DNA (Deoxyribonucleic Acid)IBA
10/2023 - 02/2002
8Triglycerides (Triacylglycerol)IBA
07/2023 - 12/2010
8Circular RNAIBA
01/2022 - 01/2017
7Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2024 - 12/2003
7AlbuminsIBA
03/2024 - 01/2018
7Indicators and Reagents (Reagents)IBA
01/2024 - 02/2014
7Protein Isoforms (Isoforms)IBA
11/2023 - 10/2009
7Sirtuin 3IBA
01/2023 - 01/2018

Therapy/Procedure

128Therapeutics
04/2024 - 02/2002
40Drug Therapy (Chemotherapy)
03/2024 - 06/2003
29Immunotherapy
03/2024 - 11/2002
25Radiotherapy
12/2023 - 05/2006
16Chemoradiotherapy
03/2024 - 07/2008
16Transplantation
02/2024 - 11/2009
14Injections
03/2024 - 01/2018
11Aftercare (After-Treatment)
03/2024 - 12/2011
7Lasers (Laser)
04/2024 - 06/2005
7Oral Administration
12/2023 - 01/2018